Peer Reviewed Studies

Efficacy of Improved Hydrogen Peroxide Against Important Healthcare-Associated Pathogens

Rutala, W.A, Gergen, M.F. and Weber, D.J. | Infection Control and Hospital Epidemiology, November (2012)

This study evaluated the efficacy of four disinfectants against drug-resistant bacteria, including a quaternary ammonium compound, a traditional hydrogen peroxide product, and two improved hydrogen peroxide products (AHP® and Clorox). The improved HP products significantly outperformed all other products tested. Although the AHP® and Clorox products showed similar efficacy, the Clorox product contains almost triple the concentration of active ingredient.

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Category: Peer Reviewed Studies

Theoretical and Experimental Aspects of Microbicidal Activities of Hard Surface Disinfectants: Are Their Label Claims Based on Testing Under Field Conditions?

Omidbakhsh N. | Journal Of AOAC International (2010)

This study addresses the disparity between disinfectant efficacy testing conditions and the actual conditions encountered in the field. The researchers compared the efficacy of a variety of disinfectant chemistries against Staphylococcus aureus and Pseudomonas aeruginosa, on both a hard surface as well as a hydrophobic (water-repelling) surface. AHP® remained wet on the surfaces for an acceptable period of time, whereas quarternary ammonium compounds and bleach did not.

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Category: Peer Reviewed Studies

Improved Eradication of Clostridium difficile Spores from Toilets of Hospitalized Patients Using an Accelerated Hydrogen Peroxide® as the Cleaning Agent

Alfa M et al. | BMC Infectious Diseases (2010)

This study compared the activity of AHP® against a different stabilized hydrogen peroxide disinfectant in terms of efficacy against C. difficile spores on toilets in a tertiary care facility. The data indicate that the AHP® product significantly outperformed the other hydrogen peroxide product, and offered at least some sporicidal activity (28% of samples were culture positive after the tests). The study highlights the safety benefits to using AHP® in place of 5000 ppm bleach.

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Category: Peer Reviewed Studies

Efficacy of Two Hydrogen Peroxide Teat Disinfectant Against Staphylococcus aureus and Streptococcus agalactiae

Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 | American Dairy Science Association (2006)

This study evaluated the efficacy of an AHP®-based teat disinfectant against Staphylococcus aureus and Streptococcus agalactiae. The AHP®-based product achieved good efficacy, without the negative effects on teat skin condition associated with other disinfectant products.

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Category: Peer Reviewed Studies

Combined Application of Simulated Reuse and Quantitative Carrier Tests to Assess High-Level Disinfection: Experiments with an Accelerated Hydrogen Peroxide®-Based Formulation

Sattar, S. et al. | AJIC (2002)

This study evaluated the efficacy of an AHP®-based high-level disinfectant against important healthcare-associated bacteria, and investigated whether efficacy would be reduced after 14 days of reuse. The results indicate that the AHP® disinfectant is effective against these bacteria, with no loss in efficacy at the end of the 14-day window.

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Category: Peer Reviewed Studies

A New Peroxide-Based Flexible Endoscope-Compatible High-Level Disinfectant

Omidbakhsh et al | American Journal of Infection Control (2006)

This study evaluated whether AHP® would be suitable as a substitute for glutaraldehyde for the disinfection of semicritical medical devices such as endotracheal tubes. The author found that AHP®'s efficacy, safety and environmental profiles position it as significantly superior to traditional high-level disinfectant chemistries.

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Category: Peer Reviewed Studies

An Accelerated Hydrogen Peroxide® (AHP®)-based Fast-Acting and Reusable Microbicide for Manual Disinfection of Heat Sensitive Semi-Critical Medical Devices

Omidbakhsh, N. & Kenny, N. | Canadian Journal of Infection Control (2008)

This study evaluated the efficacy of an AHP®-based high-level disinfectant against important healthcare-associated bacteria, and investigated whether efficacy would be reduced after 14 days of reuse. The results indicate that the AHP® disinfectant is effective against the bacteria tested, with no difference in efficacy after 14 days of reuse.

Category: Peer Reviewed Studies

Quality Control is Indispensable for Automated Dilution Systems with Accelerated Hydrogen Peroxide®

O’Neill, C. et al. (2009) | Canadian Journal of Infection Control (2009)

This study assessed the importance of quality control when using dilution systems with AHP®. By testing use dilution of AHP® at a major healthcare facility in Ontario, researchers identified several key quality issues, warranting a rigorous quality control process.

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Category: Peer Reviewed Studies

Modeling Microbial Survival in Buildup Biofilm for Complex Medical Devices

Alfa, M.J. and Howie, R. | BMF Infectious Diseases (2009)

This study compared the efficacy of AHP® and glutaraldehyde in the disinfection of bacteria in a biofilm matrix. The researchers found that biofilm was significantly more likely to build up between cycles of cleaning and disinfection when glutaraldehyde was used, possibly due to a mechanism of cross-linking between the disinfectant and biofilm. For this reason, AHP® is recommended as the better choice for biofilm decontamination.

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Category: Peer Reviewed Studies

Evaluation of Different Disinfectants on the Performance of an On Meter Dosed Amperometric Glucose-Oxidase-Based Glucose Meter

Sarmaga, D. et al. | Journal of Diabetes Science and Technology (2012)

This study evaluated whether the use of AHP® would interfere with the accuracy of glucose meters commonly used by patients with diabetes. The data indicate that there was no difference in the readings before and after the AHP® treatment was applied, suggesting that AHP® does not affect the accuracy of these meters.

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Category: Peer Reviewed Studies