Peer Reviewed Studies

Efficacy of Improved Hydrogen Peroxide Against Important Healthcare-Associated Pathogens

Rutala, W.A, Gergen, M.F. and Weber, D.J. | Infection Control and Hospital Epidemiology, November (2012)

This study evaluated the efficacy of four disinfectants against drug-resistant bacteria, including a quaternary ammonium compound, a traditional hydrogen peroxide product, and two improved hydrogen peroxide products (AHP® and Clorox). The improved HP products significantly outperformed all other products tested. Although the AHP® and Clorox products showed similar efficacy, the Clorox product contains almost triple the concentration of active ingredient.

Theoretical and Experimental Aspects of Microbicidal Activities of Hard Surface Disinfectants: Are Their Label Claims Based on Testing Under Field Conditions?

Omidbakhsh N. | Journal Of AOAC International (2010)

This study addresses the disparity between disinfectant efficacy testing conditions and the actual conditions encountered in the field. The researchers compared the efficacy of a variety of disinfectant chemistries against Staphylococcus aureus and Pseudomonas aeruginosa, on both a hard surface as well as a hydrophobic (water-repelling) surface. AHP® remained wet on the surfaces for an acceptable period of time, whereas quarternary ammonium compounds and bleach did not.

Improved Eradication of Clostridium difficile Spores from Toilets of Hospitalized Patients Using an Accelerated Hydrogen Peroxide® as the Cleaning Agent

Alfa M et al. | BMC Infectious Diseases (2010)

This study compared the activity of AHP® against a different stabilized hydrogen peroxide disinfectant in terms of efficacy against C. difficile spores on toilets in a tertiary care facility. The data indicate that the AHP® product significantly outperformed the other hydrogen peroxide product, and offered at least some sporicidal activity (28% of samples were culture positive after the tests). The study highlights the safety benefits to using AHP® in place of 5000 ppm bleach.

Efficacy of Two Hydrogen Peroxide Teat Disinfectant Against Staphylococcus aureus and Streptococcus agalactiae

Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 | American Dairy Science Association (2006)

This study evaluated the efficacy of an AHP®-based teat disinfectant against Staphylococcus aureus and Streptococcus agalactiae. The AHP®-based product achieved good efficacy, without the negative effects on teat skin condition associated with other disinfectant products.

Combined Application of Simulated Reuse and Quantitative Carrier Tests to Assess High-Level Disinfection: Experiments with an Accelerated Hydrogen Peroxide®-Based Formulation

Sattar, S. et al. | AJIC (2002)

This study evaluated the efficacy of an AHP®-based high-level disinfectant against important healthcare-associated bacteria, and investigated whether efficacy would be reduced after 14 days of reuse. The results indicate that the AHP® disinfectant is effective against these bacteria, with no loss in efficacy at the end of the 14-day window.

A New Peroxide-Based Flexible Endoscope-Compatible High-Level Disinfectant

Omidbakhsh et al | American Journal of Infection Control (2006)

This study evaluated whether AHP® would be suitable as a substitute for glutaraldehyde for the disinfection of semicritical medical devices such as endotracheal tubes. The author found that AHP®'s efficacy, safety and environmental profiles position it as significantly superior to traditional high-level disinfectant chemistries.

An Accelerated Hydrogen Peroxide® (AHP®)-based Fast-Acting and Reusable Microbicide for Manual Disinfection of Heat Sensitive Semi-Critical Medical Devices

Omidbakhsh, N. & Kenny, N. | Canadian Journal of Infection Control (2008)

This study evaluated the efficacy of an AHP®-based high-level disinfectant against important healthcare-associated bacteria, and investigated whether efficacy would be reduced after 14 days of reuse. The results indicate that the AHP® disinfectant is effective against the bacteria tested, with no difference in efficacy after 14 days of reuse.

Quality Control is Indispensable for Automated Dilution Systems with Accelerated Hydrogen Peroxide®

O’Neill, C. et al. (2009) | Canadian Journal of Infection Control (2009)

This study assessed the importance of quality control when using dilution systems with AHP®. By testing use dilution of AHP® at a major healthcare facility in Ontario, researchers identified several key quality issues, warranting a rigorous quality control process.

Modeling Microbial Survival in Buildup Biofilm for Complex Medical Devices

Alfa, M.J. and Howie, R. | BMF Infectious Diseases (2009)

This study compared the efficacy of AHP® and glutaraldehyde in the disinfection of bacteria in a biofilm matrix. The researchers found that biofilm was significantly more likely to build up between cycles of cleaning and disinfection when glutaraldehyde was used, possibly due to a mechanism of cross-linking between the disinfectant and biofilm. For this reason, AHP® is recommended as the better choice for biofilm decontamination.

Evaluation of Different Disinfectants on the Performance of an On Meter Dosed Amperometric Glucose-Oxidase-Based Glucose Meter

Sarmaga, D. et al. | Journal of Diabetes Science and Technology (2012)

This study evaluated whether the use of AHP® would interfere with the accuracy of glucose meters commonly used by patients with diabetes. The data indicate that there was no difference in the readings before and after the AHP® treatment was applied, suggesting that AHP® does not affect the accuracy of these meters.