Technical Bulletins

Efficacy of three disinfectant formulations and a hydrogen peroxide/silver fogging system on surfaces experimentally inoculated with methicillin-resistant Staphylococcus pseudintermedius

Soohoo J, Daniels JB, Brault SA, Rosychuk RAW, Schissler JR. | Veterinary Dermatology

Three disinfectants were tested against methicillin-resistant Staphylococcus pseudintermedius (MRSP), a leading cause of nosocomial infections in companion animals. AHP® achieved the greatest reduction in bacteria of the products tested. The HaloFogger fogging unit, using HaloMist disinfectant, was evaluated against the same bacteria, but produced significantly lower reductions.

Category: Technical Bulletins

Accelerated Hydrogen Peroxide® (AHP®), a Proven History of Preventing Transmission of Coronaviruses

Virox Technologies

In late 2019, an outbreak of respiratory illness in Wuhan, China was identified. It is now understood that this outbreak is associated with a Novel Coronavirus that is now identified as COVID-19. Coronaviruses are of significant concern owing to the fact they are zoonotic in nature, meaning they can infect humans and animals1. Prior to the identification of COVID-19, there were six (6) strains of Coronavirus capable of infecting humans with only two (2) strains capable of causing severe disease; severe acute respiratory syndrome (SARS-CoV) and Middle East respiratory syndrome (MERS-CoV)1.

Category: Technical Bulletins

Infection Prevention and Control Best Practices for Small Animal Veterinary Clinics

Virox Technologies Inc. | Canadian Committee on Antibiotic Resistance, 2008

This document was developed by the Canadian Committee on Antibiotic Resistance and is intended to guide clinical practice and provide assistance for decision-making on infection prevention and control issues. Furthermore, this document is designed to provide a complete and readily accessible summary of infection prevention and control best practices for small animal veterinary clinics, and is intended to be understandable to all members of the veterinary practice team.

Category: Technical Bulletins

Best Practices Document for the Management of Clostridium difficile "C. diff" in all Health Care Settings

Virox Technologies Inc. | Ontario Provincial Infectious Diseases Advisory Committee

This document was developed by the Provincial Infectious Diseases Advisory Committee (PIDAC). PIDAC is a multidisciplinary scientific advisory body who provide to the Chief Medical Officer of Health in Ontario evidence-based advice regarding multiple aspects of infectious disease identification, prevention and control. PIDAC’s work is guided by the best available evidence and updated as required. Best Practice documents and tools produced by PIDAC reflect consensus positions on what the committee deems prudent practice and are made available as a resource to the public health and health care providers.

Category: Technical Bulletins

Effects of disinfection on the molecular detection of porcine epidemic diarrhea virus

Bowman A, Nolting J, Nelson S, Bliss N, Stull J, Wang Q, Premanandan C.

Routine detection of porcine epidemic diarrhea (PEDv) is currently limited to RT-PCR testing, as it is the only test method that can directly detect PEDv. Because RT-PCR only detects the viral RNA, a positive RT-PCR result only indicates the presence of PEDv viral RNA, but does not mean viable and infectious virus is present. Accelerated Hydrogen Peroxide®(AHP®) is a relatively new yet proven technology that is capable of disinfecting PEDv but may still leave inactivated RNA strands on surfaces, and therefore has a history of producing RT-PCR positive test results. In this study AHP was tested along with a number of other disinfectant actives as agents against PEDv using RT-PCR. Positive RT-PCR results were tested to show how AHP was able to fully inactivate any remaining RNA on the surface. Therefore, AHP can be used as an alternative disinfectant that is effective against PEDv without the negative toxicity, environmental, safety and compatibility profiles.

Category: Technical Bulletins

Burden of Clostridium difficile infection on hospital readmissions and its potential impact under the Hospital Readmission Reduction Program

Virox Technologies Inc. | Chopra T. et al.

Although improved infection control efforts have been successful in decreasing the rates of many hospital-associated infections, Clostridium difficile infections (CDIs) still remain a problem. Accelerated Hydrogen Peroxide® (AHP®) is a patented disinfectant technology that is known for its effective cleaning properties as well as fast acting bactericidal and virucidal efficacy. AHP® surface disinfectants have been proven to reduce bacterial spore load on hard-non-porous surfaces .

Category: Technical Bulletins

Evaluation of disinfectants and wiping substrates combinations to inactivate Staphylococcus aureus on Formica coupons

Brown, E., Dhanireddy, K., Waldron, C., Teska, P., Eifert, J. and Boyer, R.

Three disinfectants were each paired with three wiping substrates to compare their relative efficacies against S. aureus on Formica surfaces such as those common in hospitals. Sodium hypochlorite and accelerated hydrogen peroxide (AHP®)-based products applied with the cotton or microfiber cloths, respectively, demonstrated the greatest antimicrobial efficacy overall.

Category: Technical Bulletins

Effects of contact time and concentration on bactericidal efficacy of 3 disinfectants on hard nonporous surfaces

Hong Y, Teska PJ, Oliver HF.

This study evaluated three disinfectants, including AHP®, against Staphylococcus aureus and Pseudomonas aeruginosa at a variety of off-label contact times and concentration. Invariably, reduced contact times and concentrations resulted in reduced efficacy in all disinfectants, highlighting the importance of adhering to label directions.

Category: Technical Bulletins

In-Vitro Evaluation of Topical Biocide and Antimicrobial Susceptibility of Staphylococcus pseudintermedius from Dogs

Valentine BK, Dew W, Yu A, Weese JS.

In response to the rise in antibiotic resistance, topical biocides are emerging as alternatives in the case of diseases like canine pyoderma. This study found that several topical products, including an AHP®-based shampoo, effectively inhibit growth of Staphylococcus pseudintermedius in-vitro.

Category: Technical Bulletins

UV-visible marker confirms that environmental persistence of Clostridium difficile spores in toilets of patients with C. difficile-associated diarrhea is associated with lack of compliance with cleaning protocol

Alfa M.J., Dueck C., Olson N., DeGagne P., Papetti S., Wald A., Lo E. and Harding G.

Environmental survival of antibiotic resistant organisms has been suspected to play a role in nosocomial transmission of pathogens. When patients are diagnosed with infections, they are put on isolation precautions and for pathogens such as C. difficile, the housekeeping cleaning protocols are enhanced to reduce the environmental load and potential for cross contamination and as a result the risk of acquiring nosocomial infections. In this study an ultraviolet visible marker (UVM) was used to assess the cleaning compliance of housekeeping staff for toilets in a healthcare setting. The aim of this project was to determine if a UVM could be used to determine the compliance of housekeeping staff with the twice daily cleaning protocols for patients who have been placed on isolation precautions because of CDAD (C. difficile associated diarrhea).

Category: Technical Bulletins