Technical Bulletins

Strategies to Prevent Clostridium difficile Infections in Acute Care Hospitals: 2014 Update

Virox Technologies Inc. | Infection Control and Hospital Epidemiology, June 2014, Vol. 35, No.6

Clostridium difficile now rivals methicillin-resistant Staphylococcus aureus (MRSA) as the most common organism to cause hospital associated infections (HAIs) in the United States. These historically high levels of CDI are estimated to cost US hospitals $1.0-4.9 billion per year and is responsible for an estimated 14,000-29,000i deaths annually. Therefore, measures must be taken to actively prevent cases of CDI.

The ChildSafe Guidelines: Green Cleaning Products for Schools

Virox Technologies Inc. | Grassroots Environmental Education (2010).

The increasing incidence of environmentally mediated illness in children, combined with emerging science that links many of these illnesses with exposures to chemical toxins, has precipitated an increase in “green” cleaning products for use in schools and other facilities where children spend time. Accelerated Hydrogen Peroxide® (AHP®) is a patented chemical formulation that uses chemicals that have undergone stringent toxicity testing and have been proven to be a safe and sustainable alternative to legacy chemicals ensuring that AHP formulations will meet guideline requirements.

Lab disinfectant harms mouse fertility

Virox Technologies Inc. | Macmillan Publishers Limited - 2008

The harmful effects of quaternary ammonium-based disinfectants (Quats) found in lab mice, indicates the importance of choosing a disinfectant that balances efficacy with safety, without compromising either. It is also important to consider the environmental sustainability in a disinfectant, as chemical compounds can build up over time that have the ability to contribute to unforeseen health and environmental issues.

Efficacy of eight commercial disinfectants against Microsporum canis and Trichophyton spp: infective spores on an experimentally contaminated textile surface

Moriello K, Kunder D, Hondzo H.

Dermatophytosis (ringworm), a highly contagious skin infection, is caused by fungus leading to a circular rash on animals and humans. Due to the highly contagious nature of dermatophytosis, proper disinfection of affected surfaces is essential. This study considers a relatively new yet proven chemistry, broadly used in healthcare facilities, known as Accelerated Hydrogen Peroxide® (AHP®), in contrast with current chemistries that have known shortcomings.

The Role of Environmental Surfaces in Transmitting Infections

The medical and economic toll of infections continues to escalate. Dating back to the mid-1800’s and Florence Nightingale, there has long been an understanding in the medical field regarding the importance of maintaining a clean environment. With the introduction of antibiotics the focus on infections moved perhaps more towards the cure than preventing the transmission.

Theoretical and experimental aspects of microbicidal activities of hard surface disinfectants: Are their label claims based on testing under field conditions?

Omidbakhsh, N.

Seven disinfectant products were tested against standard strains of Staphylococcus aureus and Pseudomonas aeruginosa to determine whether their label conditions could be realistically complied with in real-world applications. The findings indicate that AHP® was the sole product tested with a contact time shorter than its dwell time.

Disinfectant wipes are appropriate to control microbial bioburden from surfaces: use of a new ASTM standard test protocol to demonstrate efficacy

Sattar S.A. et al.

High-touch environmental surfaces (HTES) are being recognized increasingly for their potential to spread pathogens in healthcare and other settings. Decontamination of HTES is almost always either by a disinfectant spray and wipe procedure or by wiping with a disinfectant pre-soaked wipe (DPW). However, products marketed for this purpose are rarely tested using conditions simulating their field use, and the label claims of environmental surface disinfectants seldom include wiping action. Additionally, during routine wiping, DPW may dislodge localized contamination on HTES and transfer it to neighboring areas being wiped, posing a substantial threat to the spread of pathogenic bacteria. Accelerated Hydrogen Peroxide® (AHP®) has been proven to decontaminate surfaces without transferring acquired contamination to clean surfaces.

Evaluation of an accelerated hydrogen peroxide disinfectant to inactivate porcine epidemic diarrhea virus in swine feces on aluminum surfaces under freezing conditions

Baker K.L., Thomas P.R., Karriker L.A., Ramirez A., Zhang J., Wang C. and Holtkamp D.J.

Aluminum coupons were contaminated with porcine epidemic diarrhea virus (PEDv), and then treated with accelerated hydrogen peroxide (AHP®). Samples from these contaminated coupons were subsequently administered to live pigs. AHP® reduced, but did not eliminate, the concentration of active virus on the coupons. No pigs who ingested the inoculum treated with AHP® developed clinical signs of PEDv, indicating that AHP® can effectively inactivate the virus to acceptable levels.

Cleaning Hospital Room Surfaces to Prevent Health Care-Associated Infections

Han J.H. et al.

Healthcare-associated infections (HAIs) are the leading cause of illness and death world-wide. A multifaceted approach to preventing infection is critical to reducing the risk for HAIs as several studies demonstrate that healthcare-associated pathogens frequently contaminate the patient environment, including both porous surfaces and hard non-porous surfaces. Contaminated surfaces are a reservoir for the transmission of pathogens directly through patient contact with the environment or indirectly through contamination of health care workers' hand or gloves.

Efficacy of Green Cleaning Products with Respect to Common Respiratory Viruses and Mold Growth

Ed Light

As infection prevention and control concerns continue to move mainstream into our communities, schools, offices, etc., so too does the increased usage of cleaning chemicals and disinfectants. The increased usage of many of these chemistries has the potential to negatively impact the environment and therefore, many end users are searching for “greener” alternatives. A major concern in this trend is the implementation of cleaning products that are simply ineffective in killing certain microorganisms. The increasing prevalence of hydrogen peroxide, an environmentally preferable ingredient with limited antimicrobial efficacy on its own, has the potential to exacerbate this concern. Many manufacturers of hydrogen peroxide-based cleaners are positioning their products as effective disinfectants without validation leading to potential misperception.