Technical Bulletins

Comparing Two Disinfectants Through a Price Analysis

Hutto E.

Choosing the right disinfectant and format to fit your facilities disinfection needs is impacted by many important factors. Formats range from Ready-to-Use (RTU) spray liquid, RTU disposable wipes or dilutable concentrate solutions. Often times, concentrated disinfectants are presumed to be the more cost-effective option in comparison to RTU products, however when considering other factors such as compliance, shelf life, labor costs, compatibility, time, efficacy and convenience, these factors can highlight the benefits and overall cost savings of RTU disinfectants.

Multi-Drug Resistant Candida auris

Candida auris is an emerging multi-drug resistant yeast that poses a global health threat. Known for causing serious and sometimes fatal fungal infections in hospitalized patients, this yeast does not respond to commonly used antifungal drugs, making infections difficult to treat. Furthermore, C. auris is difficult to identify with standard laboratory methods, as such it can be misidentified in labs without specific technology. For these reasons, effective infection prevention measures, including disinfection of environmental surfaces, are an essential aspect in the prevention and control of this emerging pathogen. Currently the CDC recommends the use of a sporicidal agent to be used in suspected or confirmed cases of C. auris. However, leveraging Spaulding’s Hierarchy of Susceptibility, our position is that when used according to label directions, disinfectants with proven efficacy against fungi, such as those based on Accelerated Hydrogen Peroxide®, will be effective against this emerging pathogen.

Provincial Infectious Diseases Advisory Committee (PIDAC) Best Practices for Cleaning, Disinfection, and Sterilization In All Health Care Settings

PIDAC | Research Highlights

This document was developed by the Provincial Infectious Diseases Advisory Committee (PIDAC) and reviewed and approved by the Ministry of Health and Long-Term Care. This document is intended for health care providers to ensure that the critical elements and methods of decontamination, disinfection and sterilization are incorporated into health care facility procedures. The document describes essential elements and methods in the safe handling, transportation and biological decontamination of contaminated medical equipment / devices. The best practices for reprocessing medical equipment set out in this document should be practiced in all settings where care is provided, across the continuum of health care. This includes settings where emergency care is provided, hospitals, long-term care homes, outpatient clinics, community health centers and clinics, physician offices, dental offices, offices of allied health professionals, public health and home health care.

An evaluation of the effectiveness of sanitation procedures using an accelerated hydrogen peroxide (Accel) disinfectant to reduce virus transmission via livestock transport vehicles

Schneider P, Holtkamp D, Ramirez A, Zhang J.

Disease outbreaks within the swine industry can be devastating with mass economical costs. With the constant threat of disease emergence, industry is looking to new chemical formulations, vetted protocols, and scientific support as a front line of defense for their biosecurity. This study tests the efficacy of a relatively new yet proven chemistry that is broadly used in healthcare facilities known as Accelerated Hydrogen Peroxide® (AHP®), recognized for its superior cleaning ability and realistic contact times, ensuring disinfection has taken place

(797) Pharmaceutical Compounding-Sterile Preparations (2008)

Virox Technologies Inc. | The United States Pharmacopeial Convention

Accelerated Hydrogen Peroxide® (AHP®) is continuing to gain popularity as one of the most effective and safest disinfectant chemistries. AHP is highlighted in the United States Pharmacopeia (USP) as THE product with a perfect balance between efficacy, safety and compatibility, revealing the technologies potential within compound pharmacy. The inclusion of AHP in the most recent USP edition reinforces AHP as an accepted disinfectant in the Pharmaceutical Industry.

Evaluation of sporicidal activities of selected environmental surface disinfectants: Carrier tests with the spores of Clostridium difficile and its surrogates

Omidbakhsh N.

Clostridium difficile is an increasingly common nosocomial pathogen whose spores are very resistant to disinfectants. For disinfection to occur, it is important for a product to keep the surface wet for the entire disinfection contact time as noted on the label in order to achieve the claimed disinfection activity. Accelerated Hydrogen Peroxide® (AHP®) is a relatively new yet proven technology that was tested for its efficacy against C.difficile spores. AHP was the only chemistry that was able to achieve the contact time as specified on the label when used under real world conditions. Additionally, AHP Technology has gained a reputation for being one of the most effective and safest disinfection technologies on the market.

Diversity of Bacterial Communities of Fitness Center Surfaces in a U.S. Metropolitan Area

Mukherjee, Nabanita et al.

Public fitness centers and exercise facilities have been implicated as possible sources for transmitting community-associated bacterial infections; however, there is a lack of knowledge about the diversity of microbial communities at fitness centers. Microbial load and diversity of the environment are often implicated as a critical indicator of hygiene and cleanliness. Facility cleanliness can be achieved through cleaning and disinfection of environmental surfaces. Accelerated Hydrogen Peroxide® (AHP®) is a proven technology that has demonstrated effectiveness against the commonly found bacteria identified in this study, without compromising user safety.

Selection of the Ideal Disinfectant

Rutala W.A. and Weber D.J.

Healthcare-associated infections (HAIs) remain an important source of morbidity and mortality. A major source of nosocomial pathogens is thought to be the patient’s endogenous flora, but an estimated 20%- 40% of HAIs have been attributed to cross infection via the hands of healthcare personnel. Contamination of the hands of healthcare personnel could in turn result from direct patient contact or indirectly from touching contaminated surfaces. Healthcare personnel have frequent contact with environmental surfaces in patients’ rooms, providing ample opportunity for contamination of gloves and/or hands. Scientific literature has demonstrated that improving surface cleaning and disinfection reduces HAIs.

Modeling microbial survival in buildup biofilm for complex medical devices

Alfa M.J. and Howie R.

Flexible endoscopes undergo repeated rounds of patient-use and reprocessing. Some evidence indicates that there is an accumulation or build-up of organic material that occurs over time in endoscope channels. This “buildup biofilm” (BBF) develops as a result of cyclical exposure to wet and dry phases during usage and reprocessing. Biofilm formation has been suggested in reprocessed flexible endoscopes in spite of adequate reprocessing; however the practical effect of such biofilm on reprocessing efficacy and infection transmission is unknown. This study investigated whether BBF matrix represents a greater challenge to disinfectant efficacy and microbial eradication than “traditional biofilm” (TBF) which forms when a surface is constantly bathed in fluid. Furthermore, this study tested the effectiveness of Accelerated Hydrogen Peroxide®(AHP®) against biofilms and compared it with other chemistries with known shortcomings.

Cleanliness of portable medical equipment disinfected by nursing staff

Havill N.L. et al.

Increased attention has been focused on disinfection by housekeepers, but very little data is available on disinfection of equipment by nurses. Pathogens can reside on shared patient care equipment surfaces, across the healthcare environment. Although protocol and outline of the division of labor across departmental lines for specific tasks may exist, monitoring and providing feedback and improvement can help mitigate risk of pathogen transmission.