Technical Bulletins

Selection of the Ideal Disinfectant

Rutala W.A. and Weber D.J.

Healthcare-associated infections (HAIs) remain an important source of morbidity and mortality. A major source of nosocomial pathogens is thought to be the patient’s endogenous flora, but an estimated 20%- 40% of HAIs have been attributed to cross infection via the hands of healthcare personnel. Contamination of the hands of healthcare personnel could in turn result from direct patient contact or indirectly from touching contaminated surfaces. Healthcare personnel have frequent contact with environmental surfaces in patients’ rooms, providing ample opportunity for contamination of gloves and/or hands. Scientific literature has demonstrated that improving surface cleaning and disinfection reduces HAIs.

Modeling microbial survival in buildup biofilm for complex medical devices

Alfa M.J. and Howie R.

Flexible endoscopes undergo repeated rounds of patient-use and reprocessing. Some evidence indicates that there is an accumulation or build-up of organic material that occurs over time in endoscope channels. This “buildup biofilm” (BBF) develops as a result of cyclical exposure to wet and dry phases during usage and reprocessing. Biofilm formation has been suggested in reprocessed flexible endoscopes in spite of adequate reprocessing; however the practical effect of such biofilm on reprocessing efficacy and infection transmission is unknown. This study investigated whether BBF matrix represents a greater challenge to disinfectant efficacy and microbial eradication than “traditional biofilm” (TBF) which forms when a surface is constantly bathed in fluid. Furthermore, this study tested the effectiveness of Accelerated Hydrogen Peroxide®(AHP®) against biofilms and compared it with other chemistries with known shortcomings.

Cleanliness of portable medical equipment disinfected by nursing staff

Havill N.L. et al.

Increased attention has been focused on disinfection by housekeepers, but very little data is available on disinfection of equipment by nurses. Pathogens can reside on shared patient care equipment surfaces, across the healthcare environment. Although protocol and outline of the division of labor across departmental lines for specific tasks may exist, monitoring and providing feedback and improvement can help mitigate risk of pathogen transmission.

Evaluation of sporicidal activities of selected environmental surface disinfectants: Carrier tests with the spores of Clostridium difficile and its surrogates

Omidbakhsh N.

Clostridium difficile is an increasingly common nosocomial pathogen whose spores are very resistant to disinfectants. For disinfection to occur, it is important for a product to keep the surface wet for the entire disinfection contact time as noted on the label in order to achieve the claimed disinfection activity. Accelerated Hydrogen Peroxide® (AHP®) is a relatively new yet proven technology that was tested for its efficacy against C.difficile spores. AHP was the only chemistry that was able to achieve the contact time as specified on the label when used under real world conditions. Additionally, AHP Technology has gained a reputation for being one of the most effective and safest disinfection technologies on the market.

(800) Hazardous Drugs - Handling in Healthcare Settings (2015)

Virox Technologies Inc. | United States Pharmacopeial Convention

Accelerated Hydrogen Peroxide® (AHP®) is a Health Canada and EPA registered disinfectant which continues to gain popularity as one of the most effective and safest disinfectant chemistries in the market. AHP is highlighted in the United States Pharmacopeia (USP) as the product with a perfect balance between efficacy, safety and compatibility, revealing the technologies potential within compound pharmacy. In the latest revision of Hazardous Drugs - Handling in Healthcare Settings, hydrogen peroxide was frequently mentioned as an effective chemistry for the deactivation of hazardous drugs (HDs), which reinforces AHP as an accepted disinfectant in the Pharmaceutical Industry.

Canadian Standards of Care in Animal Shelters: Supporting ASV Guidelines

Attard E, Duncan K, Firmage T, Flemming S, Mullaly K, Pryor P, Smrdelj M, Cartwright B, Rastogi T.

Shelter facilities provide a unique challenge for cleaning and disinfection. Animals interact with surfaces within the environment in a far different way than humans and can be adversely impacted by harmful residues left behind on surfaces. Furthermore, many facilities employ volunteers who have little to no background in the safe use of chemicals. Accelerated Hydrogen Peroxide® (AHP®) offers the perfect balance between safety and efficacy, making it the ideal disinfectant chemistry for use in cleaning and disinfection of shelter facilities.

Prospective cluster-controlled crossover trial to compare the impact of an improved hydrogen peroxide disinfectant and a quaternary ammonium-based disinfectant on surface contamination and healthcare outcomes

Boyce J.M., Guercia K.A., Sullivan L., Havill N.L., Fekieta R., Kozakiewicz J. and Goffman D.

This study compared the efficacy of a quaternary ammonium compound (Quat)-based disinfectant and an accelerated hydrogen peroxide (AHP®) disinfectant when used to clean high-touch surfaces in hospital wards. Bacterial counts were significantly reduced in the AHP® trials, and high-touch surfaces yielded no growth significantly more often when AHP® was used.

CDC Guidelines for Disinfection and Sterilization in Healthcare Facilities, 2008

This document was developed by HICPAC (formerly the Hospital Infection Control Practices Advisory Committee) and reviewed and approved by the Centers for Disease Control (CDC). The Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008, presents evidence-based recommendations on the preferred methods for cleaning, disinfection and sterilization of patient care medical devices and for cleaning and disinfecting the healthcare environment. The document supersedes the relevant sections contained in the 1985 Centers for Disease Control (CDC) Guideline for hand washing and Environmental Control. Furthermore, this is the first CDC Infection Control Guidelines that includes information on Accelerated Hydrogen Peroxide® (AHP®), highlighting the advantages of AHO technology and its rapid contact time when compared to traditional disinfectant chemistries, legitimizing the use of AHP®.

Risk of Infection in the Use of Flotation Tanks

Virox Technologies Inc. | Public Health Ontario, 2016

Flotation tanks are lightless, soundproof chambers in which a person floats in a shallow depth of salt water. In recent years, the recreational use of flotation tanks has grown in popularity as a form of stress reduction. The risk of infection in the use of flotation tanks emphasizes the importance of practicing proper routine cleaning and disinfection.

Guideline to Controlling Infectious Folliculitis and Dermatophytosis in Equine

Weese J, Yu A.

Bacterial, dermatophilosis and superficial ringworm infections are common skin diseases noted in equine dermatology. The ability to recognize and accurately diagnose the skin condition is key to selecting an appropriate and successful treatment regimen. Accelerated Hydrogen Peroxide® (AHP®) is a leading disinfectant technology in the human health market and is becoming increasingly recognized as the cleaner, faster and safer disinfectant technology within the animal health market. Known for its germicidal potency, yet incredible safety profile, this guideline validates the use of AHP within the Equine market.