Technical Bulletins

Modeling microbial survival in buildup biofilm for complex medical devices

Alfa M.J. and Howie R.

Flexible endoscopes undergo repeated rounds of patient-use and reprocessing. Some evidence indicates that there is an accumulation or build-up of organic material that occurs over time in endoscope channels. This “buildup biofilm” (BBF) develops as a result of cyclical exposure to wet and dry phases during usage and reprocessing. Biofilm formation has been suggested in reprocessed flexible endoscopes in spite of adequate reprocessing; however the practical effect of such biofilm on reprocessing efficacy and infection transmission is unknown. This study investigated whether BBF matrix represents a greater challenge to disinfectant efficacy and microbial eradication than “traditional biofilm” (TBF) which forms when a surface is constantly bathed in fluid. Furthermore, this study tested the effectiveness of Accelerated Hydrogen Peroxide®(AHP®) against biofilms and compared it with other chemistries with known shortcomings.

Cleanliness of portable medical equipment disinfected by nursing staff

Havill N.L. et al.

Increased attention has been focused on disinfection by housekeepers, but very little data is available on disinfection of equipment by nurses. Pathogens can reside on shared patient care equipment surfaces, across the healthcare environment. Although protocol and outline of the division of labor across departmental lines for specific tasks may exist, monitoring and providing feedback and improvement can help mitigate risk of pathogen transmission.

Evaluation of sporicidal activities of selected environmental surface disinfectants: Carrier tests with the spores of Clostridium difficile and its surrogates

Omidbakhsh N.

Clostridium difficile is an increasingly common nosocomial pathogen whose spores are very resistant to disinfectants. For disinfection to occur, it is important for a product to keep the surface wet for the entire disinfection contact time as noted on the label in order to achieve the claimed disinfection activity. Accelerated Hydrogen Peroxide® (AHP®) is a relatively new yet proven technology that was tested for its efficacy against C.difficile spores. AHP was the only chemistry that was able to achieve the contact time as specified on the label when used under real world conditions. Additionally, AHP Technology has gained a reputation for being one of the most effective and safest disinfection technologies on the market.

(800) Hazardous Drugs - Handling in Healthcare Settings (2015)

Virox Technologies Inc. | United States Pharmacopeial Convention

Accelerated Hydrogen Peroxide® (AHP®) is a Health Canada and EPA registered disinfectant which continues to gain popularity as one of the most effective and safest disinfectant chemistries in the market. AHP is highlighted in the United States Pharmacopeia (USP) as the product with a perfect balance between efficacy, safety and compatibility, revealing the technologies potential within compound pharmacy. In the latest revision of Hazardous Drugs - Handling in Healthcare Settings, hydrogen peroxide was frequently mentioned as an effective chemistry for the deactivation of hazardous drugs (HDs), which reinforces AHP as an accepted disinfectant in the Pharmaceutical Industry.